{"id":6392,"date":"2025-09-16T12:07:34","date_gmt":"2025-09-16T07:07:34","guid":{"rendered":"https:\/\/vetnewsandviews.com\/en\/?p=6392"},"modified":"2025-09-16T12:07:35","modified_gmt":"2025-09-16T07:07:35","slug":"breakthrough-trial-prevents-breast-cancer-recurrence","status":"publish","type":"post","link":"https:\/\/vetnewsandviews.com\/en\/breakthrough-trial-prevents-breast-cancer-recurrence\/","title":{"rendered":"Breakthrough Trial Prevents Breast Cancer Recurrence"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

hiladelphia, USA (September 2025)<\/strong> \u2013 In a landmark discovery, researchers at the University of Pennsylvania have successfully prevented breast cancer recurrence by eliminating dormant tumor \u201csleeper\u201d cells\u2014the hidden cause of relapse for millions of survivors.<\/p>\n\n\n\n

For decades, dormant cancer cells lying undetectable in bone marrow have been a silent threat, reawakening years later as aggressive, metastatic disease. Now, scientists have shown that these stealthy cells can not only be tracked but also eradicated with FDA-approved drugs.<\/p>\n\n\n\n

In a Phase II federally funded clinical trial, researchers treated survivors with therapies targeting autophagy and mTOR signaling. Results were dramatic:<\/p>\n\n\n\n

80% of patients had hidden cells fully eliminated.<\/p>\n\n\n\n

Recurrence-free survival exceeded 90% after three years.<\/p>\n\n\n\n

In patients receiving combination therapy, survival reached 100%.<\/p>\n\n\n\n

\u201cThese findings mark the first real proof that dormant breast cancer cells can be safely identified and removed,\u201d said lead investigator Dr. Angela DeMichele, University of Pennsylvania.<\/p>\n\n\n\n

The study, published in Nature Medicine, could transform survivorship care. With recurrence affecting nearly 1 in 3 survivors\u2014sometimes decades after initial treatment\u2014this breakthrough offers hope for a future where breast cancer no longer returns.<\/p>\n\n\n\n

Larger clinical trials are already underway to validate these results and bring this approach into routine care.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

hiladelphia, USA (September 2025) \u2013 In a landmark discovery, researchers at the University of Pennsylvania have successfully prevented breast cancer recurrence by eliminating dormant tumor \u201csleeper\u201d cells\u2014the hidden cause of… 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