{"id":6613,"date":"2025-10-13T11:58:23","date_gmt":"2025-10-13T06:58:23","guid":{"rendered":"https:\/\/vetnewsandviews.com\/en\/?p=6613"},"modified":"2025-10-13T11:58:26","modified_gmt":"2025-10-13T06:58:26","slug":"first-detection-enzootic-nasal-tumor-virus-pakistan","status":"publish","type":"post","link":"https:\/\/vetnewsandviews.com\/en\/first-detection-enzootic-nasal-tumor-virus-pakistan\/","title":{"rendered":"First Detection of Enzootic Nasal Tumor Virus (ENTV) in Pakistan"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"800\" height=\"480\" src=\"https:\/\/vetnewsandviews.com\/en\/wp-content\/uploads\/2025\/10\/website-banner-780x480-2.jpg\" alt=\"First Detection of Enzootic Nasal Tumor Virus (ENTV) in Pakistan\" class=\"wp-image-6615\" srcset=\"https:\/\/vetnewsandviews.com\/en\/wp-content\/uploads\/2025\/10\/website-banner-780x480-2.jpg 800w, https:\/\/vetnewsandviews.com\/en\/wp-content\/uploads\/2025\/10\/website-banner-780x480-2-300x180.jpg 300w, https:\/\/vetnewsandviews.com\/en\/wp-content\/uploads\/2025\/10\/website-banner-780x480-2-768x461.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>By: Dr. Anjum Jamil, Product Manager \u2013 Jawad Impex International<\/strong><\/p>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-39c1000d0ca0e897a99996d0b206ba22 wp-block-paragraph\"><strong>Introduction<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For the first time in Pakistan, <strong>Enzootic Nasal Tumor Virus (ENTV)<\/strong> has been detected in small ruminants. This retrovirus, belonging to the family <em>Retroviridae<\/em>, is known to cause <strong>enzootic nasal adenocarcinoma (ENA)<\/strong> in sheep and goats. ENTV is a contagious and progressive disease that primarily affects the upper respiratory tract, leading to <strong>tumor development inside the nasal cavity<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Globally, ENTV has been reported from Europe, Africa, China, and India, but this is the <strong>first confirmed detection in Pakistan<\/strong>, highlighting the need for increased awareness, diagnosis, and preventive strategies in our small ruminant population.<\/p>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-a551acc8529ca2effe95436754a24e58 wp-block-paragraph\"><strong>Clinical Presentation<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Animals affected by ENTV typically show:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Persistent <strong>nasal discharge<\/strong> (serous or mucopurulent)<\/li>\n\n\n\n<li><strong>Dyspnea<\/strong> (difficulty in breathing) due to nasal obstruction<\/li>\n\n\n\n<li><strong>Loud respiratory noises<\/strong> (&#8220;snoring&#8221; or &#8220;stertor&#8221;)<\/li>\n\n\n\n<li><strong>Head shaking, sneezing, and facial deformities<\/strong> in later stages<\/li>\n\n\n\n<li>Progressive <strong>loss of condition<\/strong> despite normal appetite<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Unlike bacterial or parasitic diseases, ENTV-induced tumors are <strong>non-resolving<\/strong> and ultimately fatal.<\/p>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-2226095c618847144c726d65b412a757 wp-block-paragraph\"><strong>Significance for Pakistan<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The detection of ENTV in Pakistan is alarming because:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Sheep and goat farming is a <strong>backbone of rural livelihood<\/strong>.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">    2. ENTV causes <strong>economic losses<\/strong> through reduced productivity, weight loss, and mortality.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">    3. Farmers and veterinarians often misdiagnose it as pneumonia, bacterial rhinitis, or parasitic         infections, delaying correct action.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This discovery underlines the importance of <strong>diagnostic vigilance, veterinary training, and supportive interventions<\/strong> to safeguard animal health.<\/p>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-da4e039c74d621bc45ae4d341341cff8 wp-block-paragraph\"><strong>Management Challenges<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Currently, there is <strong>no curative treatment<\/strong> for ENTV. Control depends on:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Early <strong>diagnosis<\/strong> and <strong>culling<\/strong> of affected animals<\/li>\n\n\n\n<li>Improving <strong>biosecurity and farm hygiene<\/strong><\/li>\n\n\n\n<li>Supporting <strong>immunity and respiratory health<\/strong> of the flock<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This is where <strong>feed additives and nutraceuticals<\/strong> play a vital role.<\/p>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-link-color wp-elements-68d44cbe4c7b7b38f22242cbcd3e144c wp-block-paragraph\"><strong>Role of Innovative Feed Additives in Supportive Care<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At <strong>Jawad Impex International<\/strong>, we recognize the urgent need for products that enhance immunity, protect gut and respiratory health, and reduce the impact of opportunistic infections in ENTV-positive flocks. Some of our key solutions include:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li class=\"has-vivid-red-color has-text-color has-link-color wp-elements-8c0b9230e93e5250b6bd5247fea2c623\"><strong>Nano Selenium (3%)<\/strong><\/li>\n<\/ol>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Enhances antioxidant defense and immune response.<\/li>\n\n\n\n<li>Supports respiratory tissue integrity by reducing oxidative stress.<\/li>\n\n\n\n<li>Helps improve fertility, growth, and general disease resistance.<\/li>\n<\/ol>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-link-color wp-elements-4b4801fbeb4935b028b048c7904b0f84 wp-block-paragraph\"><strong>Butifour\u00ae (Calcium Butyrate with natural additives)<\/strong><\/p>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Strengthens gut health, improving nutrient absorption and resilience.<\/li>\n\n\n\n<li>A healthy gut means a stronger immune system to cope with viral challenges like ENTV.<\/li>\n<\/ol>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-link-color wp-elements-b639a9c444429950f5082d206df0426f wp-block-paragraph\"><strong>Zagrisorb (Mycotoxin Binder with Yeast Cell Wall)<\/strong><\/p>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Protects against immunosuppressive mycotoxins in feed.<\/li>\n\n\n\n<li>Yeast \u03b2-glucans boost immune activity, while MOS improve gut flora balance.<\/li>\n\n\n\n<li>Reduces secondary risk factors that worsen ENTV progression.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">By combining <strong>scientific research with practical farm solutions<\/strong>, our products can help farmers <strong>reduce losses, strengthen flock immunity, and support overall productivity<\/strong> in the face of new viral threats like ENTV.<\/p>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-fd065a99b9246d2a69176798600bf687 wp-block-paragraph\"><strong>Conclusion<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <strong>first detection of ENTV in Pakistan<\/strong> is both a challenge and an opportunity. It highlights the hidden viral threats present in our livestock industry, but also opens the door for better <strong>diagnostics, management strategies, and use of advanced nutraceuticals<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">With a <strong>comprehensive approach<\/strong> \u2014 including biosecurity, early detection, and innovative feed solutions \u2014 we can protect our sheep and goat industry from the devastating impact of this newly identified viral disease.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Jawad Impex International<\/strong> remains committed to <strong>supporting veterinarians and farmers<\/strong> with world-class products, ensuring healthier animals and stronger profits for Pakistan\u2019s livestock sector.<\/p>\n\n\n\n<p class=\"has-vivid-red-color has-text-color has-link-color has-large-font-size wp-elements-9cfed862ff1a09f0b9d204740a336d67 wp-block-paragraph\"><strong>References<\/strong><\/p>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li>De las Heras, M., Ort\u00edn, A., Benito, A., Summers, C., Ferrer, L. (2003). Enzootic nasal adenocarcinoma of sheep and goats: characterization of the epithelial cell population in tumors induced by ENTV. <em>Journal of Comparative Pathology<\/em>, 128(2\u20133), 137\u2013146.<\/li>\n\n\n\n<li>Cousens, C., Minguij\u00f3n, E., Dalziel, R.G., Ort\u00edn, A., Sharp, J.M., De las Heras, M. (1999). Complete sequence of enzootic nasal tumor virus, a retrovirus associated with transmissible intranasal tumors of sheep. <em>Journal of Virology<\/em>, 73(5), 3986\u20133993.<\/li>\n\n\n\n<li>Palmarini, M., Sharp, J.M. (2003). Retroviral pathogenesis in sheep and goats. <em>Veterinary Research<\/em>, 34(6), 639\u2013653.<\/li>\n\n\n\n<li>Caporale, M., Centorame, P., Giovannini, A., Sacchini, F., Di Ventura, M., De las Heras, M., Palmarini, M. (2006). Infection of lung epithelial cells and induction of pulmonary adenocarcinoma is not a property of all retroviruses. <em>Virology<\/em>, 346(1), 107\u2013118.<\/li>\n\n\n\n<li><strong>Jamil, A. (2025). First detection of Enzootic Nasal Tumor Virus (ENTV) in Pakistan: case report and implications for small ruminant health. <em>Pakistan Veterinary Journal<\/em> (Submitted\/Accepted, 2025).<\/strong><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>By: Dr. Anjum Jamil, Product Manager \u2013 Jawad Impex International Introduction For the first time in Pakistan, Enzootic Nasal Tumor Virus (ENTV) has been detected in small ruminants. This retrovirus,&hellip; <\/p>\n","protected":false},"author":2,"featured_media":6615,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"footnotes":""},"categories":[19],"tags":[2555,2552,2553,2554],"class_list":["post-6613","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-article-blog","tag-animal-health-pakistan","tag-entv","tag-enzootic-nasal-tumor-virus","tag-pakistan-livestock-disease"],"yoast_head":"<!-- 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