{"id":7977,"date":"2026-03-26T14:46:41","date_gmt":"2026-03-26T09:46:41","guid":{"rendered":"https:\/\/vetnewsandviews.com\/en\/?p=7977"},"modified":"2026-03-26T14:46:42","modified_gmt":"2026-03-26T09:46:42","slug":"heat-adaptation-genes-indigenous-chickens","status":"publish","type":"post","link":"https:\/\/vetnewsandviews.com\/en\/heat-adaptation-genes-indigenous-chickens\/","title":{"rendered":"Scientists Discover 25 Genes That Help Indigenous Chickens Survive Extreme Heat"},"content":{"rendered":"\n

Extreme heat is emerging as a major threat to the global poultry industry, especially in tropical regions where temperatures frequently reach 40\u201345\u00b0C<\/strong> and in parts of Pakistan even exceed 50\u00b0C.<\/strong> Under such harsh conditions, commercial poultry farms often face heavy losses, including high mortality rates and a decline in egg production by up to 36 percent.<\/strong><\/p>\n\n\n\n

Despite these challenges, indigenous chicken breeds continue to survive, grow, and reproduce in the same extreme environments. A new international research study has now uncovered the genetic mechanisms that make this possible.<\/p>\n\n\n\n

Breakthrough Research on Heat Adaptation in Chickens<\/h3>\n\n\n\n

An international team of scientists led by Ali Hassan Nawaz<\/strong> and Prof. Chungang Feng<\/strong> from Nanjing Agricultural University, China, has identified 25 key genes<\/strong> responsible for heat tolerance in chickens. The research has been published in the internationally recognized journal Poultry Science (Elsevier).<\/p>\n\n\n\n

The study reveals that heat resistance in chickens is not controlled by a single gene. Instead, it is regulated by a complex biological system described as a cardio-neuroendocrine signaling network.<\/p>\n\n\n\n

Global Scientific Collaboration<\/h3>\n\n\n\n

The research brought together experts from China, Pakistan, Thailand, and South Africa. Pakistan\u2019s contribution came from Dr. Nasir Mukhtar<\/strong> of PMAS Arid Agriculture University, Rawalpindi, who provided valuable insights into indigenous chicken breeds adapted to desert climates.<\/p>\n\n\n\n

Additional support was provided by researchers from Chiang Mai University, Thailand, and the University of Limpopo, South Africa, contributing genetic data and environmental expertise.<\/p>\n\n\n\n

Key Genetic Discoveries<\/h3>\n\n\n\n

Using advanced genomic tools, including selective sweep analysis, eQTL mapping, and transcriptome-wide association studies, researchers analyzed 14 different chicken breeds<\/strong> from diverse climates.<\/p>\n\n\n\n

The study identified four major regulatory genes:<\/p>\n\n\n\n

    \n
  • ATP1A1<\/strong><\/li>\n\n\n\n
  • PLCB4<\/strong><\/li>\n\n\n\n
  • RYR2<\/strong><\/li>\n\n\n\n
  • AKT3<\/strong><\/li>\n<\/ul>\n\n\n\n

    These genes act as a central control system that regulates cardiovascular function, calcium signaling, and cellular survival during heat stress.<\/p>\n\n\n\n

    Researchers found that indigenous chickens rely on a coordinated biological system connecting the heart, hypothalamus, and liver. This system helps maintain body temperature, energy balance, and survival under extreme heat conditions.<\/p>\n\n\n\n

    ATP1A1<\/strong> was identified as particularly important, showing strong links with production traits such as eggshell strength and overall egg quality. This suggests that heat tolerance and productivity are closely connected.<\/p>\n\n\n\n

    Evidence from Human Genetics<\/h3>\n\n\n\n

    The study also found that some of these genes, especially RYR2 and ATP1A1<\/strong>, perform similar functions in humans. This indicates that these heat adaptation mechanisms are conserved across species and have evolved over time.<\/p>\n\n\n\n

    Implications for Poultry Industry and Food Security<\/h3>\n\n\n\n

    With rising global temperatures due to climate change, this research offers a practical pathway for developing climate-resilient poultry breeds.<\/p>\n\n\n\n

    By selecting and breeding chickens with these 25 key genes, scientists may be able to create commercial poultry that can maintain productivity even in temperatures as high as 45\u201350\u00b0C.<\/strong> This could play a critical role in ensuring food security in regions like South Asia, Africa, and the Middle East.<\/strong><\/p>\n\n\n\n

    Publication Information<\/h3>\n\n\n\n

    The study is published in Poultry Science under the title:<\/p>\n\n\n\n

    \u201cIntegrative genomic analysis and gene expression patterns reveal a cardio-neuroendocrine signaling network for heat adaptation in geographically diverse chickens.\u201d<\/p>\n\n\n\n

    <\/p>\n","protected":false},"excerpt":{"rendered":"

    Extreme heat is emerging as a major threat to the global poultry industry, especially in tropical regions where temperatures frequently reach 40\u201345\u00b0C and in parts of Pakistan even exceed 50\u00b0C.… <\/p>\n","protected":false},"author":2,"featured_media":7978,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"footnotes":""},"categories":[21],"tags":[3624,3625,3622,3623,3279,1509],"class_list":["post-7977","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-poultry-industry-updates-and-insights","tag-climate-resilient-livestock","tag-genomics-research","tag-heat-stress-poultry","tag-indigenous-chickens","tag-poultry-farming-pakistan","tag-poultry-science"],"yoast_head":"\n25 Heat-Adaptation Genes Found in Chickens | Breakthrough Poultry Research<\/title>\n<meta name=\"description\" content=\"Scientists identify 25 genes that help indigenous chickens survive extreme heat up to 50\u00b0C. 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